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News

BSHI Conference
05-Sep-2018

The 29th Annual British Society for Histocompatibility and Immunogenetics (BSHI) Conference will take place in Cardiff at the Royal Welsh College of Music and Drama on 5th and 6th September 2018 For m..

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32nd European Immunogenetics and Histocompatibility Conference
09-May-2018

The 32nd European Immunogenetics and Histocompatibility Conference (EFI) will be held in Venice, Italy from 9th to 12th of May, 2018. The BAG healthcare Lunch-Symposium will take place on Friday, May 11th from 12:00 ..

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NEW: HLA B*27 realtime PCR testing
18-Apr-2018

From April 2018 HISTO TYPE B*27*Q kit for fast and easy detection of HLA-B*27 is available. All CWD alleles are detected in one PCR Mix and the alleles B*27:06 and B*27:09 that are not associated with Mor..

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NEW: ERY SPOT® Weak D-TYPE
01-Jul-2017

BAG Health Care would like to introduce a new product of the ERY SPOT® Weak D-TYPE, available from January 2018. The ERY SPOT® SSO system is a fast, simple and cost effective method for molecular typing of b..

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Blog

Haemolytic Reactions In Blood Transfusion
Haemolytic Reactions In Blood Transfusion
Jessica Harland - Wednesday, August 08, 2018

Haemovigilance is an important aspect of transfusion science concerning the minimization of adverse effects and adverse events. One of the more serious complications following a blood transfusion is a haemolytic transfusion reaction, where donor blood contains antibodies incompatible with patient blood. The adverse event occurs when red blood cells given during the transfusion are destroyed by the recipient’s immune system. 

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Coeliac Disease - Disease Association Testing
Coeliac Disease - Disease Association Testing
Jessica Harland - Monday, July 30, 2018

Coeliac disease is a T-cell-mediated chronic autoimmune disease which effects the absorption of nutrients in the small intestine due to surface inflammation. The symptoms are caused by disease-specific antibodies against endomysium or tissue transglutaminase, which inflict damage to the lining of the intestine upon ingestion of gluten. Commonly reported symptoms include stomach pain and cramping, nausea, ongoing fatigue, constipation, diarrhoea, weight loss, mouth ulcers and bloating.  

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Molecular Contamination Control
Molecular Contamination Control
Jessica Harland - Thursday, July 12, 2018

Polymerase chain reaction (PCR) is a highly sensitive technique to amplify a single copy of DNA into millions to billions of copies of a targeted sequence. Whilst its sensitivity is advantageous it can also create a number of issues if the correct contamination control is not followed. During PCR, even the smallest amount of contaminating DNA can be amplified resulting in the wrong template amplification and causing false positive or ambiguous results. Contamination can arise from work surfaces, equipment or reagents which have been exposed to PCR products. To minimize the risk of contamination there are several preventative methods and aseptic techniques which must be carefully performed. 

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